Jesus rejoices in the little ones (human) and in the little things (nature). He blesses the Father for revealing the grandest of knowledge to mere children instead of the learned and clever. Those who are humble and simple would be more receptive to the graces of God, rather than those who are puffed up and who are already filled up - they are too full to receive the graces as well as the knowledge of God.

Similarly, from the prophecy of Isaiah, the image of the smallest things in nature are used to describe the greatness of God and the might of God's work. The shoots and scions of a plant are very small, but from them, a huge plant will grow. In the same way, from the smallness of the stock and root of Jesse will emerge the Saviour of the world. God works wonders from smallness. Even though this Saviour may be deemed small, "His word is a rod that strikes the ruthless." (Is 11:1:4)

Furthermore, despite its smallness, it can be a great sign. "That day, the root of Jesse shall stand as a signal to the peoples." (Is 11:10) Humility can be a good example and sure sign that leads people to greater humility. Thus, smallness can be contagious. It helps to make other people small as well.